| CustomFlixCreateSpace: Self Publishing and Free Distribution for Books, CD, DVD | Publishing | North Charleston | SC | $1 - 10M |
| FstoppersFstoppers - Photography News and Community for Creative Professionals | Online Media | Charleston | SC | |
| TwitPicTwitpic - Share photos and videos on Twitter | Internet | Charleston | SC | $0 - 1M |
| Blackbaud
Fundraising for Nonprofits, Nonprofit Software – Blackbaud
| Computer Software | Charleston | SC | > $1B |
| The Post and Courierpostandcourier.com | Post and Courier | Charleston, SC. Local News, Sports and Weather | Newspapers | Charleston | SC | $100 - 250M |
| | Higher Education | Charleston | SC | > $1B |
| Compare CardsCredit Cards | Compare The Best Credit Card Offers | CompareCards.com | Financial Services | Charleston | SC | $1 - 10M |
| | Hospital & Health Care | Charleston | SC | > $1B |
| BoomTownBoomTown | Real Estate Sales & Marketing Software | Computer Software | Charleston | SC | $10 - 50M |
| | Higher Education | Charleston | IL | $10 - 50M |
| | Internet | Charleston | SC | |
| | Government Administration | Charleston | WV | $100 - 250M |
| | Broadcast Media | Charleston | SC | $1 - 10M |
| eTapestry
Fundraising and Donor Management | eTapestry | Blackbaud
| Health, Wellness and Fitness | Charleston | SC | $100 - 250M |
| | Public Safety | Charleston | WV | $100 - 250M |
| | Higher Education | Charleston | SC | $100 - 250M |
| | Primary/Secondary Education | North Charleston | SC | $1 - 10M |
| | Publishing | Charleston | SC | $1 - 10M |
| BenefitfocusOnline Benefits Enrollment Portal - Cloud Based Employee Benefits Platform | Benefitfocus | Computer Software | Charleston | SC | $10 - 50M |
| | Market Research | Charleston | WV | $0 - 1M |
| | Banking | North Charleston | SC | $100 - 250M |
| | Education Management | Charleston | SC | $500M - 1B |
| | Education Management | Bennettsville | SC | $10 - 50M |
| GreystarReal Estate Management – Investment - Development | Greystar | Real Estate | Charleston | SC | > $1B |
| The CitadelThe Citadel, The Military College of South Carolina - The Citadel - Charleston, SC | Higher Education | Charleston | SC | $100 - 250M |
| | Online Media | Charleston | SC | $10 - 50M |
| | | Charleston | WV | $1 - 10M |
| TheDigitel.comCharleston, Myrtle Beach, and Beaufort local news and features | TheDigitel | Publishing | Charleston | SC | $0 - 1M |
| | Food & Beverages | Charleston | SC | |
| | Information Technology and Services | Charleston | SC | $1 - 10M |
| | Hospitality | Charleston | SC | $0 - 1M |
| | Higher Education | North Charleston | SC | $0 - 1M |
| | Automotive | Charleston | SC | $10 - 50M |
| | Apparel & Fashion | Charleston | SC | $1 - 10M |
| | Higher Education | CHARLESTON | WV | $10 - 50M |
| | Education Management | North Charleston | SC | $1 - 10M |
| | Computer Software | CHARLESTON | SC | $0 - 1M |
| | Newspapers | Charleston | IL | $10 - 50M |
| | Wholesale | CHARLESTON | WV | $1 - 10M |
| | Internet | Charleston | SC | $10 - 50M |
| | Libraries | North Charleston | SC | $1 - 10M |
| | Government Administration | Charleston | SC | $100 - 250M |
| courtswvWest Virginia Judiciary - Supreme Court of Appeals of West Virginia | | CHARLESTON | WV | $10 - 50M |
| | Sports | Charleston | SC | $0 - 1M |
| | Consumer Services | CHARLESTON | SC | $10 - 50M |
| | Health, Wellness and Fitness | Charleston | WV | $250 - 500M |
| | Recreational Facilities and Services | Charleston | SC | $10 - 50M |
| | Government Administration | Charleston | WV | $0 - 1M |
| | Warehousing | CHARLESTON | SC | $10 - 50M |
| | Machinery | CHARLESTON | SC | $1 - 10M |
| | Restaurants | Charleston | SC | |
| SnapCapUnsecured Business Loans | Business Financing | SnapCap | Financial Services | Charleston | SC | $0 - 1M |
| | Media Production | Charleston | WV | $10 - 50M |
| Life Cycle EngineeringConsulting, Engineering, Applied Technology and Education Solutions — Life Cycle Engineering | Management Consulting | Charleston | SC | $50 - 100M |
| | Hospital & Health Care | Charleston | SC | $500M - 1B |
| | Government Administration | Charleston | WV | $0 - 1M |
| | Banking | Charleston | SC | $10 - 50M |
| The Local PalateThe Local Palate | The Local Palate is the South’s premier food culture publication. | Publishing | Charleston | SC | $1 - 10M |
| | Restaurants | Charleston | SC | $500M - 1B |
| | Nonprofit Organization Management | Charleston | SC | $0 - 1M |
| | Plastics | CHARLESTON | SC | $1 - 10M |
| | Publishing | Charleston | WV | $250 - 500M |
| | Hospitality | Charleston | SC | $0 - 1M |
| Folbot IncFolbot Folding Kayaks - Unfold New Adventures | Sporting Goods | Charleston | SC | $0 - 1M |
| Energy IncThe Energy Detective Electricity Monitor | Consumer Electronics | Charleston | SC | $1 - 10M |
| | Hospital & Health Care | Charleston | WV | $500M - 1B |
| | Computer Software | Charleston | SC | $1 - 10M |
| | Entertainment | North Charleston | SC | $0 - 1M |
| | Logistics and Supply Chain | Charleston | SC | $1 - 10M |
| | Nonprofit Organization Management | Charleston | SC | $1 - 10M |
| | Telecommunications | Charleston | SC | $1 - 10M |
| Harry BarkerDistinctive Dog Accessories & Luxury Pet Products | Harry Barker | Consumer Goods | North Charleston | SC | $0 - 1M |
| | Maritime | Charleston | SC | $10 - 50M |
| | Management Consulting | Charleston | WV | $0 - 1M |
| | Computer Software | CHARLESTON | SC | $0 - 1M |
| | Nonprofit Organization Management | North Charleston | SC | $0 - 1M |
| eatatfig.comFIG – Local Neighborhood Restaurant in Downtown Charleston, SC | Restaurants | Charleston | SC | $0 - 1M |
| | Retail | North Charleston | SC | $1 - 10M |
| | Transportation/Trucking/Railroad | Charleston | SC | $0 - 1M |
| | Retail | Charleston | SC | $0 - 1M |
| | Real Estate | Charleston | WV | $50 - 100M |
| | Airlines/Aviation | Charleston | SC | $0 - 1M |
| | Financial Services | North Charleston | SC | $1 - 10M |
| | Banking | Charleston | WV | $1 - 10M |
| | Nonprofit Organization Management | Charleston | SC | $0 - 1M |
| Charleston PRCharleston Public Relations and Marketing Consultant | Public Relations and Communications | Folly Beach | SC | $0 - 1M |
| PhishLabsSecurity Awareness Training | Email Phishing Security | Information Technology and Services | Charleston | SC | $1 - 10M |
| | Entertainment | Charleston | WV | $1 - 10M |
| | Legal Services | Charleston | SC | $0 - 1M |
| Vapor ApparelVapor Apparel | #1 for Sublimation Apparel Blanks | Buy Wholesale | Apparel & Fashion | North Charleston | SC | $1 - 10M |
| FuzzcoFuzzco | Fuzzco is a creative agency in Charleston and Portland. | Design | Charleston | SC | $1 - 10M |
| | Computer Software | Charleston | SC | $1 - 10M |
| | Investment Banking | Charleston | WV | $100 - 250M |
| Coffee KindBuy Coffee Online from Award-Winning Specialty Coffee Roasters - Coffee Kind | Food & Beverages | Charleston | MA | $0 - 1M |
| | Information Technology and Services | CHARLESTON | SC | $1 - 10M |
| | Government Administration | North Charleston | SC | $0 - 1M |
| | Primary/Secondary Education | CHARLESTON | SC | $0 - 1M |
| | | Charleston | SC | $0 - 1M |
| | Local Business | CHARLESTON | SC | > $1B |
| | Environmental Services | Charleston | SC | $0 - 1M |
